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Ampoule Production Line

Clean. Compliant. Continuous Ampoule Production

Ampoule Production Line

Reliable Ampoule Production Line Manufacturer, Over 1,000 Projects Delivered

The LIENM ampoule production line is a state-of-the-art system designed for the production of 1-20ml ampoules. Capable of handling over 20 pharmaceutical processes, the line integrates advanced technologies to ensure high efficiency, product safety, and precise manufacturing. Key processes include ampoule filling, ampoule packaging, spray filling, water filling, ultrasonic washing, ampoule cleaning, pre-heating, sterilization, cooling, filling, and sealing.

 

LIENM offers customized ampoule filling lines and ampoule packaging lines to meet specific customer needs, providing a one-stop solution from design and installation to training and after-sales support. Our team ensures smooth operation and optimal product quality throughout the entire process.

 

Built with polished SS316L/304 stainless steel, all contact parts meet GMP standards for hygiene and easy cleaning. From raw material feeding to final product discharge, the entire process is streamlined for efficiency and minimal manual handling.

 

LIENM has successfully executed over 1,000 on-site projects for ampoule production lines worldwide. We offer turnkey perfume manufacturing solutions tailored to your formulas, production goals, and market needs.

  • Versatile Ampoule Handling for 1-20ml Sizes
  • Energy-Efficient Washin
  • Cross-Contamination Prevention
  • Precision Filling with Servo System
  • Reliable Ampoule Discharging
  • FDA-Approved Sterilization Function

Our Range of Ampoule Production Lines

LM-YSF Mobile High-Shear Mixer with Pneumatic Lift

LM-YSF mobile pneumatic lifting disperse high shear mixer

LM-YSJ Pneumatic Lifting High Shear Mixing Machine

LM-YSJ mobile pneumatic lifting homogenizer high shear mixer (1)

LM-YSH Industrial High Shear Mixer for Shampoo & Liquid Soap

Homogenizing Mixer Emulsifier Machine for Shampoo & Liquid Soap Production

Automatic Perfume Bottle Filling, Washing & Capping Line

perfume production line

LM-SG-B Semi-Automatic 4-Head Perfume Filling Machine

1-4 head perfume filling machine with pneumatic mixing tank

LM-JBJ-A 200L Liquid Detergent Mixing Machine

LM-JBJ-D 250L electric heating liquid wash tank
1 2 3 4 5 6 7 8 9 10 11 12 13

Explore Our Projects

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LIENM Project: Semi-Automatic Lip Gloss Filling Machine
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LIENM Project: Semi-Automatic Lip Gloss Filling Machine
150L Mobile Sealed Mixing and Storage Tank LM-YM
LIENM Project: 150L Mobile Sealed Mixing & Storage Tank LM-YM
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LIENM Project: 150L Mobile Sealed Mixing & Storage Tank LM-YM
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LIENM Project: Flat Bottle Semi-Automatic Labeling Machine
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LIENM Project: Flat Bottle Semi-Automatic Labeling Machine

Explore Our Videos

Frequently Asked Questions

1. What is an ampoule production line?

An ampoule production line is a fully automated system designed to manufacture, fill, and seal glass ampoules used for liquid pharmaceuticals. It integrates multiple processes such as washing, sterilizing, filling, sealing, and inspection into a continuous workflow.

 

2. What are the main components of an ampoule production line?

A complete ampoule production line consists of several integrated units, each performing a critical step in the production process:

  • Ampoule Feeding System: Automatically arranges and loads empty glass ampoules onto the line for continuous operation.

  • Washing Machine: Uses ultrasonic cleaning and multiple water/air jets to clean the inside and outside of ampoules thoroughly.

  • Sterilization Tunnel: Applies dry heat to sterilize ampoules, ensuring a contamination-free environment before filling.

  • Liquid Filling Machine: Precisely fills the ampoules with the required volume of liquid product, using peristaltic or piston pumps.

  • Flame Sealing Station: Uses high-temperature flames to hermetically seal the ampoules after filling, preventing contamination or leakage.

  • Visual Inspection System: Automatically checks for particles, fill levels, cracks, or cosmetic defects to ensure product quality.

  • Labeling and Packaging Unit: Applies labels and prepares ampoules for secondary packaging, ensuring traceability and presentation.

3. What sizes of ampoules can the line handle?

The line can usually handle ampoules ranging from 1ml to 20ml. Change parts are available for different sizes, and adjustments can be made to accommodate various neck and body dimensions.

4. What types of filling systems are available?

Ampoule production lines can be equipped with different filling systems based on the product’s viscosity, sterility requirements, and filling accuracy:

  • Peristaltic Pump Filling: Ideal for sterile and low-viscosity liquids; minimizes contamination risk due to no direct contact with product.

  • Piston Pump Filling: Suitable for medium to high-viscosity products; ensures accurate volume control with adjustable stroke.

  • Time-Pressure Filling: Best for consistent, free-flowing liquids; relies on controlled air pressure and time for dosing.

All filling methods are designed to ensure high precision, clean operation, and minimal product waste.

5. What is the filling accuracy of the machine?

Most modern ampoule filling machines offer a high accuracy rate of ±0.5% to ±1%, depending on the fill volume and type of pump used.

7. Is the ampoule line compliant with GMP standards?

Absolutely. The entire line is designed according to Good Manufacturing Practices (GMP), with materials and construction suitable for cleanroom use, including stainless steel surfaces and sanitary piping.

 

9. Are CIP/SIP systems available?

Yes. Clean-In-Place (CIP) and Sterilize-In-Place (SIP) functions can be integrated for automatic cleaning and sterilization of fluid pathways and filling nozzles, reducing contamination risk and downtime.

 

10. Can the production line be customized?

Yes. Ampoule production lines can be fully customized to meet your specific operational and regulatory requirements. Customization options include:

  • Ampoule size range – Support for different diameters and lengths (e.g., 1ml to 20ml or more)

  • Filling volume – Adjustable filling heads for precise dosing per your product specifications

  • Cleanroom layout compatibility – Designs adapted to your facility’s cleanroom zoning and material/personnel flow

  • Output requirement – Scalable speed and throughput to match small-batch or high-volume production

  • Integration – Seamless connection with upstream or downstream equipment such as:

    • Freeze dryers (lyophilizers)

    • Visual inspection systems

    • Cartoning or tray packing units

This flexibility ensures the line fits both current production needs and future expansion.

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